Albright a venit cu un vaccin pentru cancer la fetiţele de clasa a treia

nu stiu care a fost intentia dar suna ironic si de prost-gust.

In USA si in statele UE este acest vaccin obligatoriu ? Sau macar a fost administrat o perioada mai lunga de timp si pe un numar mare de subiectzi ? Se cunosc efectele secundare ?
Sau fetitzele noastre vor fi OBLIGATORIU (?!) cobai pentru firmele producatoare, la care babatia o fi angajata pe post de "consultant militar", conform experientzei ei cu Kosovo ?...

The retail price of the vaccine is $120 per dose

1.)
Results from an average of three years of follow-up from the FUTURE I and FUTURE II clinical trials of Gardasil®, a vaccine that protects against the two types of human papillomavirus (HPV) that are responsible for 70 percent of all cases of cervical cancer, have been published in the May 10, 2007, New England Journal of Medicine. Earlier data from the FUTURE II trial led to the FDA approval of Gardasil in June of 2006.
The FUTURE I study randomly assigned 5,455 women between the ages of 16 and 24 to receive either a three-injection course of Gardasil vaccine or placebo. For women who had not previously been exposed to HPV 16 or 18, the efficacy of the vaccine was 100 percent in "preventing vaginal, vulvar, perineal, and perianal intraepithelial lesions or warts associated with the vaccine-type HPV." (See the journal abstract).
In an intention-to-treat analysis, which included women who had previously been exposed to HPV 16 or 18, the vaccine efficacy was 73 percent against all grades of external anogenital or vaginal lesions and 55 percent against all grades of cervical lesions related to those HPV types. (An intention-to-treat analysis is one in which all the participants in a trial are analyzed according to the intervention to which they were allocated, whether they received it or not. Such analyses mirror the noncompliance and treatment changes that are likely to occur when the intervention is used in everyday practice.)... (continuare)

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...The FUTURE II study randomly assigned 12,167 women between the ages of 15 and 26 to receive either a three-injection course of Gardasil vaccine or placebo. For women who had not previously been exposed to HPV 16 or 18, the vaccine prevented 98 percent of high-grade cervical intraepithelial neoplasia related to those HPV types. (See the journal abstract.)
In an intention-to-treat analysis, which included women who had previously been exposed to HPV 16 or 18, vaccine efficacy was 44 percent against high-grade cervical disease caused by HPV types 16 or 18. As in the FUTURE I trial, "[v]accination did not appear to alter the course of cervical lesions related to HPV 16 or HPV 18 or of infection present at the time of randomization," explained the authors.
The vaccine reduced the rate of all cervical lesions in all patients regardless of prior HPV exposure, including lesions caused by HPV types not included in the vaccine, by 17 percent.
"An interim analysis of vaccine trial data submitted to the FDA showed a disproportionate, but not statistically significant, number of cases of grade 2 or 3 cervical intraepithelial neoplasia related to nonvaccine HPV types among vaccinated women," stated Drs. George Sawaya and Karen Smith-McCune from the University of California, San Francisco, in an accompanying editorial. "Updated analyses of data from these ongoing trials will be important to determine the effect of vaccination on rates of preinvasive lesions caused by nonvaccine HPV types."

Additional reliable information from the National Cancer Institute can be found at HPV (Human Papillomavirus) Vaccines for Cervical Cancer.
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II.)
Positive interim results for a candidate vaccine to prevent persistent infections by human papillomavirus (HPV) types 16 and 18 were published in the June 30, 2007, issue of The Lancet (see the journal abstract). The vaccine Cervarix® was 90 percent effective in preventing grade 2 or 3 cervical intraepithelial neoplasia (CIN2+) that contained DNA from either virus type.
The results come from a large international trial of 18,644 women aged 15-25 sponsored by the drug's manufacturer, GlaxoSmithKline Biologicals (see the protocol summary). The trial design called for analysis of early results after 23 cases of CIN2+ were detected. Two of these cases were among the 9,258 women receiving the vaccine, and 21 were among the 9,267 controls who received a hepatitis A vaccine. The mean follow-up time was 14.8 months.
In an editorial, Drs. Jessica A. Kahn of the University of Cincinnati and Robert D. Burk of the Albert Einstein College of Medicine in New York wrote, "These interim data are encouraging." But they noted that the paper does not provide information about the public health impact of vaccination "in real world settings" because the report does not provide estimates of the reduction in overall rates of CIN2+. They stress that vaccination of young adolescents is likely to have the greatest public health benefit, but that continued screening will still be required after vaccination.
A separate phase III trial testing Cervarix, cosponsored by the National Cancer Institute with support from the National Institutes of Health's Office for Research on Women's Health and the Costa Rica Ministry of Health, is now underway in Costa Rica. This trial should provide additional information about the public health impact and efficacy of the vaccine.

Studiile lor spun ca efectul unei doze este de doar 4 ani si ca nu se poate renuntza la examinarile periodice. De asemenea, ca vaccinarea nu are efect asupra subiectzilor deja infectatzi ! Cum asigura sistemul rromanesc de sanatate examinarile periodice ACUM si IN VIITOR, la numarul de subiectzi pe care vrea sa-i fortzeze sa se vaccineze ? Se considera ka kancerul de kol uterin are cauze sociale si economice. Ce face sistemul rromanesc de sanatate AKUM pentru PREVENTZIE ?